The Blind Diabetic Patient

Blind registration is available for those patients with visual
acuity of less than 3/60 in their better eye or gross field defects,
affording some financial help and social service support.
 
Patients with a visual acuity of less than 6/60 in their better eye
are eligible for registration as partially sighted. They must be
registered by an ophthalmologist using the BD8 form.

Printing  in braille is valuable but many diabetic patients have impaired
fine sensation in their fingertips, making it difficult for them to
read it. Insulin “pens”, in which palpable clicks correspond to
units of insulin are valuable for blind patients.

Surgery In Diabetic Patients ,How To Be Safely Managed

Management of insulin treated diabetes during surgery
The chief principle of diabetic management through any crisis
in which patients cannot eat or drink for any reason is to
continue insulin administration. 

The best method is to give the insulin by continuous intravenous infusion either by infusion
pump or directly from the drip bag.
 
For operations in which a patient is likely to be maintained
on a drip for more than 12 hours a regimen is needed which can
be continued for an indefinite period.

Again there are two methods of administering the insulin: a variable rate infusion
using a pump, or if this is not available, a glucose insulin-infusion.
Note:
 
• The rate of intravenous infusion must depend on the clinical
state of the patient with regard to the volume depletion,
cardiac failure, age, etc.
 
• Potassium replacement is required.
 
• If the blood glucose is persistently above 10 mmol/l the
infusion should be changed to 0·9% saline.
 
• Blood glucose should be monitored every one to two hours
during surgery and regularly postoperatively.
 
• Try to maintain the blood glucose concentration in a safe
range—6·0-12 mmol/l.
 
• Regular (at least daily) electrolyte measurements are required.
After recovery: changing to subcutaneous insulin
Once the patient starts to eat and drink conversion back to
subcutaneous insulin injections is undertaken as follows.
 
• Always change to subcutaneous insulin before breakfast and
never in the evening so that adequate supervision can be
assured.
 
• Stop the insulin pump 30 minutes after the first
subcutaneous insulin injection.
 
• Insulin regimen and dose: if the previous regimen is known
then this should be given; if the patient is still in bed or
unwell the total dose may need to be 10 to 20% more than usual. 

If the patient was not previously taking insulin,
predicting the requirement is not easy and the amount needs
adjustment from day to day. 

Initially use insulin 30-40 units
daily in divided doses given four times daily.
Patients with hyperglycaemia often relapse after conversion
back to subcutaneous insulin. When this happens there are
three possible approaches.
 
• Give additional doses of soluble insulin at any of the four
injection times (before meals or bedtime).
 
• Add an intravenous insulin infusion temporarily while
continuing the subcutaneous regimen until the blood
glucose concentration is satisfactory.
 
• Revert completely to the intravenous regimen, especially if
the patient is unwell.
Surgery in Type 2 diabetes
 
Management of diabetic patients treated with diet or oral
hypoglycaemic agents is more straightforward, so long as the
diabetes is well controlled.
If the random blood glucose value is less than 12 mmol/l:
 
• omit the tablet on the day of surgery
 
• check the blood glucose concentration before and soon after
the operation; if the blood glucose value is more than
12 mmol/l start soluble insulin.
If the diabetes is poorly controlled (random blood glucose
greater than 12 mmol/l)
 
Management of insulin treated diabetes during day surgery
Patients with insulin treated diabetes requiring an anaesthetic
for relatively minor operations or investigative procedures
(for example, barium radiological examinations, cystoscopy,
endoscopy, etc.) can be treated as day cases without hospital
admission provided that:
 
• the procedure is undertaken in the morning first on the list
(if the procedure is performed first on an afternoon list, a
light breakfast is taken after half the normal insulin dose,
followed by regular blood glucose monitoring)
 
• the procedure does not exceed approximately one hour in
duration
 
• the patient will be able to eat and drink within one hour of
the procedure
 
• the patient is able to self-monitor blood glucose and adjust
insulin appropriately.
The blood glucose should be rechecked before discharge. If
significant problems with diabetes control persist, then hospital
admission may be required after all.

Smoking and Diabetes

The addiction of smoking is now well established. 
Its harmful effects are numerous, and include a substantial increase in
cardiovascular and peripheral vascular disease as well as the
best known consequences of lung cancer and chronic
obstructive pulmonary disease. 

In diabetes, higher rates of both
nephropathy and retinopathy have been well documented.
 
Nicotine replacement therapy using proprietary sublingual
preparations, chewing gum, self adhesive patches, or
alternatively amfebutamone tablets can help, especially if used
in conjunction with the counselling which is provided by
smoking clinics.

Serious And Unserious Risks Of Insulin Injection


Many patients develop some blurring of vision soon after
starting insulin, which makes reading difficult. 

This is due to a
change of lens refraction, and it corrects itself within two to
three weeks.

Patients should be advised that this may occur,
both to avoid extreme anxiety which they may experience, and
to stop the needless purchase of new glasses.

Transient oedema
of the feet is not uncommon during the first few weeks of
insulin treatment.
Insulin treatment

Fatty lumps at injection sites are common, and occasionally
so large as to be unsightly. 

Their cause is not known but they
sometimes develop if injections are repeatedly given over a very
limited area of skin. For this reason it is best to vary the site from
day to day.

They are rarely troublesome, but once present they
tend to persist; the occasional very large fatty tumour may even
require surgical removal. 

Furthermore if insulin is repeatedly
injected into a fatty lump, the rate of absorption may be delayed
and this may have some adverse effect on blood glucose control.
 
Fat atrophy at injection sites is now very rare.
 
Red itchy marks at injection sites after starting insulin are
also rare, and if they do occur usually disappear spontaneously.
If they are very troublesome, adding hydrocortisone to the
insulin bottle so that each dose contains about 1 mg eliminates
the problem. 

Insulin allergy causing urticaria still occurs from
time to time though it is certainly a very infrequent event:
investigation by skin testing and desensitisation may be needed.
Abscesses at injection sites are also remarkably rare

Risk factors of Type 2 diabetes2

1-Birthweight and Type 2 diabetes

Recent observations suggest a relationship between low
birthweight and the development in middle age of insulin
resistance, Type 2 diabetes, and coronary artery disease. Those
who are smallest at birth and largest at one year of age are most
at risk.

2-Genetics of Type 2 diabetes

Type 2 diabetes has a strong genetic component, manifest in
the high concordance of diabetes in monozygotic twins,
familial clustering and differences in prevalence between
ethnic groups. An increasing number of specific genetic
defects are becoming recognised and some are described
below.

3-Type 2 diabetes in children and young people
Hitherto, childhood diabetes was witnessed in some ethnic
minorities and in those with the rare inherited MODY
syndromes described below.

Growing recognition now exists of
a substantial increase of this disease in the prosperous
industrialised nations. In the United States, between 8% and
45% of recently diagnosed cases of diabetes among children
and adolescents are Type 2, and the problem is increasing.
It is most likely to occur at 12 to 14 years of age, more
frequently in girls, and is strongly associated with obesity,
physical inactivity and a family history of Type 2 diabetes.
 
When young people of lean physique are discovered to have
Type 2 diabetes, it is important to attempt to identify whether
they may represent those with LADA and thus in need of
insulin. There is also evidence that in approximately
one-quarter of such patients diabetes is due to a
specific genetic defect including those of the MODY group
described below or other rare genetic syndromes.

4-Dominantly inherited Type 2 diabetes (MODY)

Seven genetic syndromes, three of which are shown in the
box at the top of page 2, cause MODY—defined as an early
onset of dominantly inherited Type 2 diabetes. 

Two (or at the very least one) members of such families should have been
diagnosed before 25 years of age, three generations (usually
first-degree) should have diabetes, and they should not
normally require insulin until they have had diabetes for more
than five years.

--Mitochondrial diabetes

Mitochondrial diabetes and deafness is a rare form of diabetes
maternally transmitted, and is related to the A3243G
mitochondrial DNA mutation. 

Diabetes is diagnosed in the fourth to fifth decades, usually in thin patients with symptoms.
Patients respond better to sulphonylureas than to diet alone.
Diabetic microvascular complications do occur.

--Insulin resistant diabetes
Some rare insulin resistant states exist in which hundreds or
even thousands of units of insulin may be ineffective. They are
often associated with lipodystrophy, hyperlipidaemia, and
acanthosis nigricans. Type A insulin resistance is due to genetic
defects in the insulin receptor or in the post-receptor pathway.
 
Type B insulin resistance occurs as a result of IgG
autoantibodies directed against the insulin receptor; it is
often associated with other autoimmune disorders such as
systemic lupus erythematosis, and it is much commoner in
women of African descent. 
Management of these conditions
can be very difficult and specialist texts should be consulted